Views: 0 Author: Site Editor Publish Time: 2023-09-30 Origin: Site
Known as Large Volume Parenteral (LVP), which usually refers to liquid sterilization preparations with a volume greater than or equal to 50ml and directly injected into the body by intravenous drip, the packaging forms include glass bottle, plastic bottle, non-PVC soft bag and vertical soft bag and other packaging forms; large infusion, tablets, liquid injections, powder injections and capsules are collectively referred to five important preparations in the global pharmaceutical industry. According to its clinical use, large infusions can be divided into fluid balance infusions, antibiotics infusions, nutritional infusions and other therapeutic infusions. They are mainly used to supplement body fluid, electrolytes and nutrition, and can be used as plasma substitutes to maintain blood pressure;
1.Overview
The production process of large infusions mainly includes "two-step preparation method(produced by two machines) " and "one-step preparation method (produced by one machine)" , the core equipment includes bag making machine, raw material transmission device, liquid dispensing system, washing, filling and sealing production line, water bath sterilization cabinet, sterilization logistic system, light inspection and packaging machine, etc.
2.The core process system of IV Fluid Solution
(1)Core process system
The core process system includes?filling system, liquid distribution system, sterilization system and other equipment and systems,?the filling system can be divided into the following types:
Glass bottle IV production linkage line;
Soft bag IV production line;
Plastic packaging BFS production line;
Plastic bottle IV production line;
(2)Past packaging system
The past packaging system mainly includes packaging processes such as lamp inspection/leak inspection, labeling /boxing, cartoning/palletizing, etc;
(3)Cleanroom system
Mainly includes architectural decoration, pipeline engineering, HVAC engineering and electrical engineering systems,etc;
(4)Utility
The utility mainly includes water treatment system, air conditioning unit, nitrogen generation system, air pressure system, steam boiler and other equipment and systems
